SS-31

Global Peptide Sciences supplies SS-31 peptide to laboratories across Australia, supporting studies into mitochondrial function, cellular energy pathways and oxidative stress research.

SS-31, also known as elamipretide, MTP-131 and Bendavia, is a synthetic tetrapeptide with the sequence D-Arg-Dmt-Lys-Phe-NH2, where Dmt is 2′,6′-dimethyltyrosine. It is studied for its ability to localise at the inner mitochondrial membrane and bind cardiolipin, a phospholipid central to electron transport chain organisation and mitochondrial structure.

Each batch is produced under controlled manufacturing conditions and undergoes independent laboratory verification, supporting consistent, repeatable results across analytical testing. A Certificate of Analysis is available on request for every order.

What Is SS-31?

Many researchers ask what is SS-31 and what does SS-31 do in laboratory models, given how often it appears in mitochondrial research literature.

SS-31 has an alternating aromatic and cationic design that allows it to enter cells and concentrate at the inner mitochondrial membrane, where it binds reversibly to cardiolipin. In preclinical work it has been examined for effects on cristae structure, electron transport chain function, ATP production and the formation of reactive oxygen species. Elamipretide is the name used in the clinical literature, and the two names refer to the same molecule.

SS-31 Peptide Benefits Explored in Research

Within controlled laboratory settings, research connected to SS-31 peptide benefits commonly looks at areas such as:

• Mitochondrial function and membrane stability studies
• Cellular energy production and ATP-related pathways
• Oxidative stress and reactive oxygen species research
• Cardiolipin interaction studies
• Cellular respiration and cristae structure models
• Ageing and metabolic pathway modelling

These points reflect laboratory observation only and are not intended as claims about therapeutic outcomes. Clinical evidence is narrow and mixed: a Phase 3 trial of elamipretide in primary mitochondrial myopathy did not meet its primary endpoints (Neurology, 2023).

Research Areas of Interest

• Studies into inner mitochondrial membrane interaction
• Investigation of cardiolipin-related mitochondrial stability
• Comparative research on cellular respiration and ATP pathways
• Oxidative stress response and cellular stress models

Product Information

• Compound: SS-31 (Elamipretide)
• Classification: Mitochondria-targeting tetrapeptide
• Sequence: D-Arg-Dmt-Lys-Phe-NH2
• Other names: Elamipretide, MTP-131, Bendavia
• Molecular formula: C32H49N9O5 (approximately 639.8 g/mol)
• CAS number: 736992-21-5
• Form: Lyophilised powder (white to off-white)
• Purity level: 98% or above (HPLC verified)
• Testing: Independent third-party laboratory verification, CoA available on request
• Storage: Store dry at -20°C for long-term storage
• Quantity: 10 mg per vial

SS-31 Reconstitution

Researchers reconstituting SS-31 for laboratory use typically follow standard laboratory protocols for combining lyophilised peptides with an appropriate sterile diluent prior to further analytical handling. Global Peptide Sciences does not provide reconstitution instructions intended for self-administration, and all reconstitution should be carried out in accordance with your own laboratory’s established procedures and safety documentation.

Why Researchers Study SS-31

Laboratories examining mitochondrial biology frequently reference SS-31 for its defined interaction with cardiolipin and its use across oxidative stress, cellular respiration and ATP models. As a single, well-characterised sequence, it suits controlled studies in which the compound identity can be verified batch by batch.

Researchers comparing mitochondrial research tools can explore the longevity research category or read the MOTS-c research summary, which covers a mitochondrial-derived peptide with a different mechanism.

Buy SS-31 in Australia

Researchers looking for ss31 for sale can source batch-documented material through Global Peptide Sciences, with independent Certificates of Analysis available for every order.

Laboratories searching for ss-31 peptide Australia can rely on a consistent supply chain backed by HPLC or LC-MS verification as reported by the testing laboratory. Anyone who wants to buy SS-31 can review the batch report first, checking the compound name, batch number and method, and keeping purity data separate from identity data.

Global Peptide Sciences offers consistent quality control at every stage of supply, and researchers can browse the full catalogue to view other research compounds available alongside SS-31.

Research Use Only

This compound is supplied strictly for laboratory research use and is not approved for human or animal consumption.